She is a graduate of the Fryderyk Chopin Academy of Music in Warsaw.
As a laureate of the young talent competition in Słupsk, she received a French government scholarship to study in Paris, where she perfected her skills with Huguette Dreyfus and Keneth Gilbert. Then she began studying at the Geneva Conservatory in the harpsichord class of Christiana Jaccottet, which she graduated with the first prize.
In 1983 she won the international harpsichord competition in Bruges, which opened her many concert stages in Europe. She has performed at many music festivals including in France, Germany, Switzerland, Italy, Poland, with ensembles such as Ensemble 415 of Chiara Banchini, Lausanne and Geneva Chamber Orchestras, Orchester de la Suisse Romande or The Chamber Orchestra of Europe. She has made many disc, radio and television recordings. Her musicological research of the seventeenth century repertoire allowed, among others for the first recording of works by J. J. Fux and cantatas by Nicolo Porpora with Artur Stefanowicz (for Naxos), which were met with great reception by music critics.
Dorota Cybulska-Amsler also gives concerts in Poland, she performed among others at festivals Wratislavia Cantans or in Łańcut, at the Royal Castle in Warsaw and Wawel, as a soloist and as a chamber musician with such soloists as Jadwiga Rappé or Artur Stefanowicz.
She is a professor of harpsichord class at the Geneva Conservatory.
Music critics emphasize in Dorota Cybulska-Amsler performance her "excellent virtuosity and perfect mastery of rubato art and Italian fantasy ornamentation" (Neue Zurcher Zeitung), "thrilling and dynamic play" (Repértoire), "a game full of temperament and freedom combined with great attention to style" (Musical Movement), "virtuosity giving each song a specific color, an extremely rhythmic and pulsating game that puts the listener into choreographic freesia" (Diapason).